{"id":143,"date":"2015-06-18T09:42:14","date_gmt":"2015-06-18T04:12:14","guid":{"rendered":"http:\/\/doctorsquiz.com\/updates\/?p=143"},"modified":"2015-06-26T23:38:13","modified_gmt":"2015-06-26T18:08:13","slug":"high-yield-point-for-biochemistry-2015-2","status":"publish","type":"post","link":"https:\/\/doctorsquiz.com\/updates\/2015\/06\/18\/high-yield-point-for-biochemistry-2015-2","title":{"rendered":"HIGH YIELD POINT FOR BIOCHEMISTRY 2015"},"content":{"rendered":"

HIGH YIELD POINT FOR BIOCHEMISTRY 2015<\/p>\n

\"BIOCHEMESTRY\"<\/a><\/p>\n

IMPORTANT POINT ABOUT Amino Acid .<\/p>\n

Glycine: \u2022 smallest amino acid. inhibitory neurotransmitter in spinal cord (blocked by toxm in tetanus), synthesis of heme and collagen and bile salts and acids<\/p>\n

Alanine: \u2022 alanine cycle during fasting. major substrate for gluconeogenesis (transarninated mto pyruvate)<\/p>\n

Valine: \u2022 essential A..A.. \u2022 branched-chain amino acid.&gt; not degraded in liver. \u2022 utilized by muscle.<\/p>\n

\u2022 increased in maple syrup urine disease<\/p>\n

Leucine: \u2022 essential A.A… \u2022 branched-chain amino acid. \u2022 not degraded in liver. \u2022 kerogenic, \u2022<\/p>\n

utilized by muscle, \u2022 increased in maple syrup urine disease<\/p>\n

Isoleucine: \u2022 essential .A…\/\\.\u2022 \u2022 branched-chain amino acid, \u2022 not degraded in liver. \u2022 utilized by<\/p>\n

muscle, \u2022 increased in maple S)’TUp urine disease<\/p>\n

Methionine: \u2022 essential A.A. \u2022 polypeptide chain initiation, \u2022 methyl donor (as S\u00b7adenosyl methionine)<\/p>\n

Proline: \u2022 helix breaker. \u2022 only amino acid with side chain attached to a-amino group. \u2022 hydroxylation in collagen aided by ascorbic acid, \u2022 binding site for cross-bridges in collagen Phenylalanine: \u2022 essential A.A. \u2022 increased in phenylketonuria (PKC). \u2022 aromatic side chains: increased in hepatic coma<\/p>\n

Trypropban: \u2022essential AA, \u2022 serotonin. niacin, and melatonin precursor. \u2022 aromatic side chains:<\/p>\n

increased in hepatic coma<\/p>\n

Cvsteiue: \u2022 forms disulfide bonds,\u2022 component of glutathione, an important antioxidant in RBCs<\/p>\n

(deficient in G6PD deficiency}<\/p>\n

Serine: \u2022 single-carbon donor: converted into glycine when carbon removed. \u2022 phosphorylatcd by<\/p>\n

k.nases<\/p>\n

Threonine: \u2022 essential A..A. \u2022 phosphorylated by kinases<\/p>\n

Tyrosine: \u2022 precursor of catecholamines, melanin, thyroid hormones. \u2022 phosphory lated by<\/p>\n

kinases: important in second messengers. \u2022 aromatic side chains: increase in hepatic coma. \u2022 must be supplied in diet in phenylketonuria<\/p>\n","protected":false},"excerpt":{"rendered":"

HIGH YIELD POINT FOR BIOCHEMISTRY 2015 IMPORTANT POINT ABOUT Amino Acid . Glycine: \u2022 smallest amino acid. inhibitory neurotransmitter in spinal cord (blocked by toxm in tetanus), synthesis of heme and collagen and bile salts and acids Alanine: \u2022 alanine cycle during fasting. major substrate for gluconeogenesis (transarninated mto pyruvate) Valine: \u2022 essential A..A.. \u2022…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[28,37,5,29,7],"tags":[97,46,49,96,52,110,118,101,111,107,99,115,112,98,100,116,114,113,60,64,120,121,65,108,109,117,119,68],"class_list":["post-143","post","type-post","status-publish","format-standard","hentry","category-aipgmee","category-dnb-cet","category-dq-online-notes","category-fmge","category-upsc-cms","tag-aiims","tag-aipgmee","tag-dermatology","tag-dnb-pdcet","tag-fmge","tag-forensic-medicine-questions-medicine","tag-free-pg-mock","tag-high-yield-notes-physiology-dnb-cet","tag-internal-medicine","tag-latest-mcq-in-anatomy-microbiology","tag-mock","tag-notes","tag-online-medicine-notes-microbiology-notes-ophthalmology","tag-online-mock-test","tag-online-notes","tag-online-notes-pathology","tag-ophthalmology-notes","tag-ophthalmology-question","tag-orthopedic","tag-psm","tag-psm-online-notes","tag-psm-question","tag-psychiatry","tag-psychiatrynotes","tag-psychiatryquestions-forensic-medicine","tag-questions","tag-radiology-questions","tag-upsc-cms"],"yoast_head":"\nHIGH 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